Recent Progress on the [3+2] Cycloaddition Route for the Synthesis of All-Carbon Quaternary Stereocentres

Abstract Construction of all-carbon quaternary centres is an important task in organic synthesis. In spite the challenges associated with Csp3–Csp3 bond construction a sterically constrained environment, significant advances have been made this area. Among latter, both catalytic and noncatalytic [3+2] cycloaddition approaches gained wide attention recently. This short review summarizes reactions reported during period 2016–2022 for synthesis molecules possessing one or more stereocentres.